eosin disodium
2,4,5-7-Tetrabromofluorescein disodium salt
CAS: 548-26-5;17372-87-1
Molecular Formula: C20H6Br4Na2O5
eosin disodium - Names and Identifiers
eosin disodium - Physico-chemical Properties
| Molecular Formula | C20H6Br4Na2O5 |
| Molar Mass | 691.85418 |
| Density | 1.02g/mLat 20°C |
| Melting Point | >300°C |
| Boling Point | 682.3℃ at 760mmHg |
| Flash Point | 11°C |
| Water Solubility | freely soluble |
| Solubility | Soluble in water, fairly soluble in alcohol, insoluble in ether |
| Appearance | Red with blue crystal or brown powder |
| Color | Reddish |
| Maximum wavelength(λmax) | 514nm |
| Merck | 14,3603 |
| BRN | 3586809 |
| pKa | 2.9, 4.5(at 25℃) |
| PH | 9.2 (10g/l, H2O, 20℃) |
| Storage Condition | Store at RT. |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Sensitive | Easily absorbing moisture |
| MDL | MFCD00133309 |
| Use | Used as adsorption indicator, etc |
eosin disodium - Risk and Safety
| Risk Codes | R11 - Highly Flammable R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R39/23/24/25 - R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R41 - Risk of serious damage to eyes R22 - Harmful if swallowed R36 - Irritating to the eyes R10 - Flammable |
| Safety Description | S7 - Keep container tightly closed. S16 - Keep away from sources of ignition. S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S24/25 - Avoid contact with skin and eyes. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S39 - Wear eye / face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| UN IDs | UN 1230 3/PG 2 |
| WGK Germany | 1 |
| RTECS | LM5850000 |
| TSCA | Yes |
| HS Code | 32041200 |
| Toxicity | LD50 orally in Rabbit: > 2000 mg/kg |
eosin disodium - Reference
| Reference Show more | 1. Zhang Liwei, Kang Jingjing, Li Yueqin, etc. Histopathological changes of canine uterus with pyometra [J]. Heilongjiang Journal of Animal Husbandry and Veterinary Medicine (second half month), 2020, 000(002):70-71,148-149. 2. Huang Chunyang, si Lifang, di lan, et al. Effects of octylphenol on the development and histological structure of epididymis, seminal vesicle and prostate in mice [J]. Progress in Animal Medicine, 2013, 29 (02):48-51. 3. Fang Xin, Li hailing, Hu Yueling, etc. Mechanism of kidney damage and oxidative stress induced by Di (2-ethylhexyl) phthalate in mice [J]. Chinese Journal of Preventive Medicine, 2014. 4. Jin Zhuhao, Cui Yunqiu, Sun Jingxin, Jin Guangyu, whole Jishan. Preparation and evaluation of liposomes loaded with magnetic iron oxide nanoparticles [J]. Journal of Yanbian University (Natural Science Edition), 2020,46(04):326-332. 5. Jayachandran, Muthukumaran, et al. "Isoquercitin ameriorates hyperglycomia and regulatory key enzymes of glucose metabolism via insulin signaling pathway in streptozotocin-induced diabetic rats." European journal of pharmacology 829 (2018): 112-120.https:// 6. [IF=4.432] Muthukumaran Jayachandran et al."Isoquercetin ameliorates hyperglycemia and regulates key enzymes of glucose metabolism via insulin signaling pathway in streptozotocin-induced diabetic rats."Eur J Pharmacol. 2018 Jun;829:112 7. [IF=3.407] Ya-Ping Jiang et al."Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage."Chem-Biol Interact. 2020 Jan;315:108869 8. [IF=4.379] Gong Gu et al."Salivary protein 7 of the brown planthopper functions as an effector for mediating tricin metabolism in rice plants."Sci Rep-Uk. 2022 Feb;12(1):1-13 |
eosin disodium - Introduction
& & Eosin Y is a xanthogen dye used for differential staining of connective tissue and cytoplasm. In histopathology, it is used as a regaining agent after hematoxylin and before methylene blue. It is also used as a background stain in contrast to a nuclear stain. Eosin Y disodium salt has been used to determine sperm motility. The swollen and stained sperm is thought to have died. In the corneal epithelium, it has been used in the process of immunostaining.
Last Update：2022-10-16 17:26:13
eosin disodium - Reference Information
| overview | water-soluble eosin Y is a chemically synthesized acid dye that dissociates into negatively charged anions in water and binds with positive amino cations of proteins to stain the cytoplasm, cytoplasm, red blood cells, muscle, connective tissue, eosinophilic granules, etc. are stained to varying degrees of red or pink, in sharp contrast to the blue nucleus. |
| application | eosin is a good dye for cytoplasm. It is generally used with hematoxylin or other dyes such as Meilan. |
| use | Eosin Y is an acid dye that dyes the cytoplasm pink (eosinophilic). It is one of the commonly used dyeing reagents in tissue and cytochemistry. It is often used with hematoxylin (a basic dye, the nuclei are dyed purple-blue (basophilic)) and used in combination (HE staining method). In immunohistochemical experiments, it is often used as a lining reagent to facilitate the observation of tissue and cell structure. Used as adsorption indicator, etc. Biochemical research Used as a biological stain. It is also used as an adsorption indicator for precipitation titration to determine Br-, I-, SCN-, MoO, Ag, etc. Used as a developer for the determination of Ag +, Pb2 +, Mn2 +, Zn2 +, etc. biological staining agent, peptide, protein, protoplasm, alkaline phosphatase, etc. Photometric determination of silver (sub-micrograms); Wright stain component, used to detect blood cells; Adsorption indicator, titrating bromine, iodine, fluorine plasma |
| category | toxic substances |
| toxicity classification | poisoning |
| acute toxicity | abdominal cavity-rat LDL0: 500 mg/kg; Oral-mouse LD50: 2344 mg/kg |
| flammability hazard characteristics | thermal decomposition to discharge toxic sodium oxide and bromide smoke |
| storage and transportation characteristics | warehouse ventilation and low temperature drying |
| extinguishing agent | water, dry powder, dry sand, carbon dioxide, foam, 1211 extinguishing agent |
| color index | 45380 |
| biological field application | Treating age-related macular degeneration,burns,cancer,diabetes,obesity,dental bone defects,gastroesophageal reflux disease,prostate cancer,viral diseases; stents; wound-healing materials |
| EPA chemical information | information provided by: ofmpub.epa.gov (external link) |
Last Update：2024-04-09 01:59:59
Supplier List
Product Name: Fluorescein Impurity 30 Request for quotation
CAS: 17372-87-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
CAS: 17372-87-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: 2,4,5-7-Tetrabromofluorescein disodium salt Request for quotationCAS: 17372-87-1
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: 2,4,5-7-Tetrabromofluorescein disodium salt Request for quotationCAS: 17372-87-1
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Product Name: 2,4,5-7-Tetrabromofluorescein disodium salt Request for quotation
CAS: 17372-87-1
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 17372-87-1
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Spot supply
Product Name: Eosin Y sodium salt water soluble Visit Supplier Webpage Request for quotationCAS: 17372-87-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: EOSIN Request for quotation
CAS: 17372-87-1
Tel: 13998106873
Email: 297303255@qq.com
Mobile: 13998106873
QQ: 297303255
Send QQ message
CAS: 17372-87-1
Tel: 13998106873
Email: 297303255@qq.com
Mobile: 13998106873
QQ: 297303255
Product Name: Fluorescein Impurity 30 Request for quotation
CAS: 17372-87-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
CAS: 17372-87-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: 2,4,5-7-Tetrabromofluorescein disodium salt Request for quotationCAS: 17372-87-1
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: 2,4,5-7-Tetrabromofluorescein disodium salt Request for quotationCAS: 17372-87-1
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Product Name: 2,4,5-7-Tetrabromofluorescein disodium salt Request for quotation
CAS: 17372-87-1
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 17372-87-1
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Spot supply
Product Name: Eosin Y sodium salt water soluble Visit Supplier Webpage Request for quotationCAS: 17372-87-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: EOSIN Request for quotation
CAS: 17372-87-1
Tel: 13998106873
Email: 297303255@qq.com
Mobile: 13998106873
QQ: 297303255Send QQ message
CAS: 17372-87-1
Tel: 13998106873
Email: 297303255@qq.com
Mobile: 13998106873
QQ: 297303255
View History